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Mustachius_Grumpius@thelemmy.club to Technology@lemmy.worldEnglish · 3 days ago

Stem cells reverse stroke damage and restore movement in mice

www.sciencedaily.com

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Stem cells reverse stroke damage and restore movement in mice

www.sciencedaily.com

Mustachius_Grumpius@thelemmy.club to Technology@lemmy.worldEnglish · 3 days ago
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Stem cell transplants helped regenerate stroke-damaged brain tissue in mice, producing new neurons and restoring lost motor function. The treatment also improved blood vessels, inflammation, and the blood-brain barrier, raising hopes that a similar approach could eventually help repair the human brain after stroke.
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  • obsolete@lemmy.dbzer0.com
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    23 hours ago

    A lot of things seem to work on mice.

    • jumping redditor [they/them]@sh.itjust.works
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      17 hours ago

      some might even work on humans, if we didn’t have ethics boards slowing us down

      • Kairos@lemmy.today
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        11 hours ago

        Cave Johnson-ass line.

  • GreenKnight23@lemmy.world
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    2 days ago

    wow. now imagine we made this discovery in 2006 and stemcell research wasn’t hindered by christofascists.

  • HugeNerd@lemmy.ca
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    2 days ago

    It’s a good time to be a sick mouse.

  • 404found@lemmy.zip
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    2 days ago

    I would like to see a how long scientists can keep a mouse alive using all the medical breakthroughs they have tested for mice.

  • leanleft@lemmy.ml
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    3 days ago

    related research:

    https://www.scmp.com/news/china/science/article/3368614/chinese-drug-loberamisal-extends-stroke-treatment-window-6-hours-2-days

    Chinese drug loberamisal extends stroke treatment window from 6 hours to 2 days

    “The large-scale multicentre phase 3 trial found that 70 per cent of patients who received loberamisal intravenously within two days of a stroke regained complete functional independence – an increase of 13 percentage points over standard care alone.”

    • tpihkal@lemmy.world
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      2 days ago

      So many people scoff at Traditional Chinese Medicine, but they’ve made some huge advancements in modern times!

      • Crit@lemmy.wtf
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        2 days ago

        What part of this is “traditional”? You just read Chinese and assumed martial arts and alchemy or something?

  • Canajan@piefed.ca
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    3 days ago

    Any progress in stroke research is helpful. After seeing the aftermath of a couple family members having strokes, to say it’s life changing isn’t adequate. Truly terrible.

  • Waterpumpee@lemmus.org
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    3 days ago

    Nice, still waiting for teeth regrowth, colonoscopy not involving fingers up my ass or a diet drug available for me tho. Feels like this shit wont hit market until the planet has been literally cooked.

    • Ostfriesentee@feddit.org
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      2 days ago

      Teeth regrow trials are coming up. Probably gonna hit the market in the 2030s.

    • LastYearsIrritant@sopuli.xyz
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      2 days ago

      You can already poop in a box and mail it off instead of fingers up the ass. – https://www.cologuard.com/

      GLP-1 is already a diet drug that’s available to most people.

      2/3 of your hopes already exist. Maybe not for everyone, maybe it’s out of your price range, but they exist.

    • Somecall_metim@lemmy.dbzer0.com
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      3 days ago

      And by then it’ll only be available for the rich.

    • SilverFlame@lemmy.world
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      3 days ago

      GLPs are coming down in price, I’ve seen them as low as $130/mo. I lost 20 pounds in the first three weeks. Its slowed to about 1-2 per week now but it is steady.

    • MonkderVierte@lemmy.zip
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      3 days ago

      or a diet drug available for me tho

      There is. Eat more fibers and veggies.

  • whyNotSquirrel@sh.itjust.works
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    3 days ago

    Is there some kind of interview to find a mouse that suffered from stroke?

    Actually, I maybe don’t want to know the reality

    • tempest@lemmy.ca
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      3 days ago

      Biotech companies breed mice for specific models. It wouldn’t surprise me to learn that they offer a mouse that has high probability to stroke.

      Or just they just use magnets apparently (How do they work?)

      https://cri.utsw.edu/ge-lab-has-developed-a-groundbreaking-method-to-study-ischemic-stroke-in-mice/

      • SaveTheTuaHawk@lemmy.ca
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        3 days ago

        It wouldn’t surprise me to learn that they offer a mouse that has high probability to stroke.

        No. They block the carotid artery.

      • Darkenfolk@sh.itjust.works
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        3 days ago

        It wouldn’t surprise me to learn that they offer a mouse that has high probability to stroke.

        Niccccee

    • GingaNinga@lemmy.world
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      3 days ago

      They probably induce it then treat it to see what happens

  • tpihkal@lemmy.world
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    3 days ago

    A lot of money being wasted to find cures for mice. Maybe they should work on finding cures for people instead.

    • whyNotSquirrel@sh.itjust.works
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      3 days ago

      I always thought that the /s was a stupid thing, but judging from the down votes on your comment, I guess it’s a necessity

      • SaveTheTuaHawk@lemmy.ca
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        3 days ago

        They have a point. Mouse model research translation to human disease has a poor track record. Mouse model labs spin in circles between models and never try to translate into humans. Some diseases stall for decades in models.

        The mouse’s brain plasticity is orders of magnitude higher than a human’s.

      • AwesomeLowlander@sh.itjust.works
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        3 days ago

        I have seen many people hold this opinion unironically.

    • Neverclear@lemmy.dbzer0.com
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      3 days ago

      Yes, this research would move so much faster if we simply induced strokes in people and injected them with stuff to see what happens… /s

      • AwesomeLowlander@sh.itjust.works
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        3 days ago

        I think tpihkal just volunteered

    • einkorn@feddit.org
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      3 days ago

      Do you volunteer to have a stroke induced so researchers then can test their treatment?

      • SaveTheTuaHawk@lemmy.ca
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        3 days ago

        they come to clinic every hour in a big city.

        • einkorn@feddit.org
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          2 days ago

          Nurse: “Sir, would you like to try this new and experimental treatment, or do you prefer proven methods?” Stroke victim: “Hhhrrrngn!” Nurse: “I’m sorry, what was that?” Stroke victim: "Hhhhhhhrhghn!!! Hrhh … " *dies*

          Great idea, Sherlock!

    • GingaNinga@lemmy.world
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      3 days ago

      I spent a career in research and I can tell you that mice are excellent models for discovery, AMA

      • SaveTheTuaHawk@lemmy.ca
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        3 days ago

        mice are excellent models for discovery

        Not really. What’s the translate rate to humans? 9%?

        Mice can model some diseases well, but they are not universally good models.

        • GingaNinga@lemmy.world
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          3 days ago

          Not universal, for example we use zebrafish for spine defect models since mouse spine has an odd curve/hunch that doesn’t line up as well. But for general metabolism/pathology/embryonic development they do a great job of mimicking human disease under the microscope. Its not always 1:1 but we learn a lot from these little guys.

      • rmuk@feddit.uk
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        3 days ago

        Why does my left bollock look like jackfruit suddenly?

        • AwesomeLowlander@sh.itjust.works
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          3 days ago

          According to Freud, because your mum had a face like a jackfruit and you’re secretly lusting for her.

  • beep@piefed.world
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    3 days ago

    Actual article, dated Sep-2025.

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