Lsd is often distributed and consumed via small paper squares called “tabs” that’s made on blotter paper. The paper is thick like cardstock. Sometimes with colorful psychedelic artwork printed on it.
The lsd is diluted in a solution and the paper is soaked in the solution.
The tiny microscopic lsd crystals deposit on the paper. The blotter paper is divided into 1cm squares. Correction. 5mm squares
Lsd is neutralized by many chemicals , including chlorine (found in tap water) and stomach enzymes. It cannot be swallowed and still have an effect. Unless mixed with other compounds. This property was for dmt/ayuhasha and not lsd. Apologies. Chlorine can neutralize LSD and is found in tap water but I can’t find the resource for how much chlorine is in an average ml of tap water and how much is needed to neutralize 100ug LSD on a paper tab, right now, so I’ll retract that statement until I feel like digging more for the research on it.
To take LSD, a person will place squares (typically one square is 1x 100ug dose) of the paper on the tounge or under it. And hold for about 5 -15 minutes. Some people take more than one. It can’t kill you. There is no overdose . But it can lead to accidents in high doses that can kill you. So it’s not risk free even if health risks are low.
Also I said ug. Not mg. The lsd drug is very unique in that it has high potency at micrograms. Fentanyl is another drug that has that property . But it is rare.
The lining of the mouth (mucus membranes) allows for easy transfer of the drug into the blood stream. That’s true for a lot of drugs actually.
This is why lsd has such a unique drug delivery method though. It can’t be swallowed and it should be used in very small doses.
Lsd is also very resistant to degredation.
Oxygen, sunlight, and neutralizing chemicals like chlorine can degrade it. But if it’s stored properly it can last a very very long time. This is another rare property it has. Many other drugs degrade even when stored in air tight containers in dark and cool environments (like opiates).
It’s also clear, tasteless, and no odor.
I’m a perception researcher and , of course, this would be a drug on my radar. So I know quite a bit about it but I’m not a pharmacologist , I’m a cognitive researcher. I’ve given a lecture on psychedelics. It’s a fascinating topic.
Also I’m generally interested in psycho-pharmacology because , well, it’s interesting.
If you want to learn more interesting facts about LSD and other psychedelics, ask away.
**Guy in picture has two tabs (squares of blotter paper) on his tongue and is wearing sunglasses because lsd dialates your pupils and makes your eyes sensitive to light.
LSD absolutely can be swallowed, I don’t understand where all these myths come from and how they keep being propagated over decades and decades when it is a very simple thing looking it up.
Also, LSD is not crystallizing onto blotter. It is absorbed into the paper fibers from a solution. That is not how crystallization works.
Jesus there is more… Chlorine can degrade LSD under certain conditions, but trace chlorine in tap water does NOT reliably neutralize it in vivo.
Lsd is also very resistant to degredation.
LSD is chemically fragile. It degrades with light, oxygen, heat, acids, bases, and oxidizers. What you are saying is the opposite of how chemists describe LSD.
Incorrect about acid in the stomach. Most DOX and nbome chems are neutralized by stomach acid and during the mid 2010 acid drought swallowing tabs was considered the simplest way to avoid unwanted DOX trips.
Source: the hundreds of tabs that I swallowed and still had a good time
Edit: Tons of chemicals are active on the hundred microgram scale. Most benzos, nearly all psychedelics, a handful of antipsychotics ect. And if we go active at >10mg, which is impossible to dose without a .000 scale, the list gets even bigger. I appreciate the attempt at an informative post but it’s got a few dangerous points of misinformation.
I’m concerned that somebody giving lectures about this topic is as uninformed as you seem to be. Have you taken acid? The subjective experience is as important as the objective. It’s like listening to my cop uncle talk about weed but couched in academia.
I took DOC back in the 00s (on purpose) and it was an extremely wild 20-some hours. Second weirdest thing I’ve done (the weirdest is Foxy by a WIDE margin,) but I still had a relatively good time due to having a great and comfortable set and setting. By hour ten, I was VERY ready to be done.
I was too poor to care, been on plenty of non acid trips on chems that lasted wayyy too long. Some were really fun, some were abject terror. Never got to try foxy sadly. MXE was the strangest chem I’ve tried and holey hell, I turned into an interdimentional worm crawling through the multiverse. It was super overwhelming.
I never tried MXE! I wanted to as I have enjoyed ket in the past, but the times I was offered MXE, I just eas not in the right headspace/environment.
Foxy is fucking insane. It had the normal visual and auditory hallucinations, but it’s the only thing I’ve ever tried that gave me full on temporal distortions. My partner-at-the-time and I were listening to familiar music. The music would get lower in pitch and streeeetch out, each individual note playing for longer and longer, until the tone went back to normal and the notes stopped being played for so long. When it was low and slow, our bodies got soooo heavy, we would just lay on the floor. When the notes got fast and higher pitched, our bodies would be light with energy. VERY weird stuff.
Most drugs/medicines are taken in higher doses because the body filters or neutralizes the compounds so much that only a small portion gets into the blood.
That’s still different.
Even if the total quantity of the drug is small in the system once it gets there, it’s not the same as how LSD works. The drug, likely because of its similarity to serotonin and size , is readily absorbed into the blood stream and passes the blood brain barrier easily. It is not filtered out to a small percentage of it’s original dose like most drugs/medicines.
You surely are aware of this ?
There are very few drugs that can work in small dosages like LSD. As I said, fentanyl is one.
Drugs like DMT /Ayahuasca also can’t be ingested unless they are mixed with a maoi inhibitor.
Most psychedelic research chemicals (nbome) are much different than lsd with different pharm and effect properties.
It’s possible that LSD is released more quickly on the tongue than nbome drugs. So as soon as it hits the tounge the drug is delivered. I don’t think there is research on this. But I’ll look into it.
I do know that the first trip was caused by a small contact of the drug on someone’s hand. That the cleaned off immediately. And it was enough time to absorb a substantial amount of the drug.
I heard women would put on lipstick and smear LSD on the front and kiss police during protest to dose them.
If That happened it might support a very fast delivery.
I can’t find the source right now to verify the story. I’ll keep looking. Maybe I have details wrong. Maybe it was Charles Manson instructing women to do this. Does this story sound familiar to anyone ? I’ll have to find the source and verify.
But my point is.
This idea that it’s not neutralized in the stomach is false. There is plenty of research on that.
Look up Clonazepam, I’m not going to argue with somebody that is as confidently incorrect as you are. I have a decade and a half of subjective experience and personal research into the chemicals I have put into my body, and spent countless hours talking with people that know even more than I do. Yes, LSD is very active in small amounts. So are plenty of other chemicals and calling it unique because of that is incorrect.
Also, stomach acid does nothing to neutralize LSD in any meaningful way, please stop saying that. You’re entire last 2 paragraphs are unsubstantiated myths and things only squares believe. The amount of LSD that Hoffman splashed on his hand likely contained thousands of doses.
I HAVE EATEN HUNDREDS IF NOT THOUSANDS OF HITS OF LSD AND SWALLOW ALMOST EVERY SINGLE ONE OF THEM. SWALLOWING LSD DOES NOT PREVENT IT FROM WORKING. I WILL GIVE YOU TABS TO FUCKING TRY IF YOU WANT
Yes, but… it’s really hard to stay focused. Everything is kinda awesome to look at, so I have forgotten about the stars and zoned on my surroundings or my hand or a hundred other things. I like tripping in the woods or at the beach best personally.
Novelty is a common effect that people don’t talk about much.
Essentially it makes everything seem new and novel.
What’s interesting is, in the brain there is a specific spike in electrical activity (called event related potential, or ERP) that happens when you look at something new and unexpected. Some call it the novelty indicator. Designated P3a.
You can measure it with eeg equipment (electrodes on the scalp).
I’d be really interested to see if that ERP is happening more on LSD. It might shed more light on the mechanisms of the drug. If it doesn’t happen, then it would challenge the theory of what the P3a is.
I personally think LSD has a lot of potential to be used to research perception processing in the brain.
Too bad it’s basically impossible to get approval to use it for that reason.
Nowadays is hard to find 100ug doses. The minimum I had found is 150ug. Anything over 400ug isn’t LSD but Nbomb that is dangerous and should be avoided.
Ugh I do not miss 25i. Put a blotter on my tongue, taste it IMMEDIATELY, spit that shit out.
(This might have been mentioned and crooner definitely already knows this, but to others interested: LSD has zero taste at all. It just tastes like the paper it’s on (or gummy, faint grain alcohol if you’ve got a vial, etc)
I gave up on LSD because it lasted way too long and finished not enjoying it, until talking with a friend I commented that I also hated the sour flavor of it and he was like dude that was nbomb not LSD. Then he gave me some actual LSD and it was way more pleasure experience, not as high, but didn’t extend as long and the landing was confortable.
Honestly, damn. That sounds like a very interesting topic. If I wanted to learn more what resources would you recommend? (preferably textbooks/articles)
Textbooks don’t really exist about this stuff, unless you’re like a pharmacology student and reading at that level.
Erowid also has free versions of PiHKAL and TiHKAL, Alexander Shulgin’s two books which are fucking awesome
I would take whatever this wall-of-text person is saying with a grain of salt. Erowid, in and of itself, isn’t a scientific source, but if you go to a page for any specific chemical, you’ll find a list of links that include scientific studies in journals, etc. as well as primary sources like experiences.
You know there isn’t much in a single location aside from Wikipedia.
In textbooks I’ve come across , there is discussion of the pharmacology properties or a brief note about counter culture and general effects.
There is limited research on the drug as it’s been black listed for almost 50 years and even now, it’s primarily only researched for terminally ill people/mental health. Only a handful of those studies exist and none use double blind controls so the science quality is poor.
I myself am not convinced it has mental health benefits due to the way the drug works. It does however have strong suggestive effects meaning the drug itself promotes placebo/expectation effects.
The lecture I put together for my class (perception and sensation ) pulled info from a wide range of resources.
However there is one organization trying it’s best to do modern research and they have done some MRI studies. There was also a study on LSD and synesthesia which sheds a lot of light into the mechanisms. MAPS is the organization.
https://maps.org/
They have videos on YouTube with researchers discussing the research and studies they have done.
But they mostly focus (last few years at least) on it’s use in mental health.
The drug property information I know about is mostly pulled from old research from the 60s before the research bans. A lot was done on animals to understand dosage and half life. The cascade effects of how this drug works are still not really understood. We do know that the drug is similar in structure to serotonin. But there are still a lot of unknowns.
Let me dig around for my resource links. I have a few interesting studies I found when preparing the lecture, including the synesthesia one, and I’ll organize it all and I’ll put a link up to a g drive with it.
The lecture I did was 3 hrs long about hallucinations with a chunk dedicated to psychedelics. It did rely on other lecture materials to understand or otherwise id just put it up. (It was the final lecture for the class so it referred back multiple times to previous lessons). But maybe I can re-write it a bit. I’ve honestly been thinking of turning it into a video for a while because there are so few resources out there that review it more broadly. And a hell of a lot of misinformation about hallucinations and psychedelics.
Basically this lecture was on hallucinations and the primary causes and how each of these causes relies on the same root changes in brain processing.
For instance. You are driving on a country road at night. Vigilant to look for deer. Multiple times you were sure you saw an animal near the road but soon realized it was a fence post. Or an old glass bottle reflecting your headlamps. But for a split moment you did see an animal there before you corrected the perception.
What ultimately caused that is what causes hallucinations in other situations. Like schizophrenia and drug use.
So we circle around neuroscience, psychiatry, physiology, and pharmacology. As well as cultural impacts influencing the experience of hallucinations or psychedelics.
This is getting long. Apologies. The lecture is 3 hrs and relies on many other hours of information. It’s a big topic.
I don’t lecture about how much acid you should drop or how to prepare for a trip. I give a lecture on the cognitive and physiological changes the drug causes.
I use scientific resources.
Other people are welcome to use personal stories and opinions to inform themselves but we don’t use anecdotes in academia because none of them can be verified and are heavily subjective.
Doesn’t mean they don’t have value. Doesn’t mean the information is false.
The definition of a scientific resource is a RESOURCE with scientific observations and reporting that is peer reviewed or has some official review process like a university website with scholars writing the information that is verified by other scholars.
It’s the review process by people who are authorities on the topic that make that distinction. Scholars. Other scientist.
A comment on social media and anecdotal websites hosting forums is not a scientific resource. It’s opinions.
As I said earlier. Something doesn’t have to be scientifically validated to be true or real.
But it does have to be science to be science.
More specifically, experiments must use the scientific method and specific research statistic computations to support hypotheses which then are used to create theories.
Erowid does not have a review process where a senior scientist reviews any of the things posted on it.
Neither does Lemmy or faceb9ok,
Why is review so important?
Because humans are biased and our own subjective interpretation of patterns and events is not objective.
Just to illustrate some of the ways our thinking and interpretation of events is flawed, see cognitive biases on wikipedia.
None of us, and I mean literally no one, is immune from these problems. Not me. Not you.
It’s why the only way we know anything for sure is through scientific methods of investigation. And even those aren’t full proof against bias.
I’m sorry that you don’t like the very basic explanation I gave of the properties of a drug you like. Some how that’s offensive to you.
I don’t know what to tell you.
I did get a few minor facts mixed up and i corrected them in the text. I Left in the original text and I crossed it out so that people could see I made a mistake and fixed it. Nothing I said was a huge big mistake about the drug. I misquoted the size of the tabs (10mm vs 5mm) and I was mistaken about it being neutralized in the stomach.
My gawd. Lock me up and send me a $500 fine. Jesus.
Maybe reflect on why it’s so important to you that your narrative of what the drug is, is being attacked from simple facts about how it works.
Why do you care how it works ?
Why are you so invested in this?
Why does it make you angry when someone explains the drug from a scientific perspective ?
If you don’t want to hear the scientific perspective then just ignore it.
Don’t even have to go that far. LSD variants like 1V-LSD can be purchased on the clear web with a credit card. Took about 1 week to be delivered from Canada to the US, and was the most potent acid I’ve ever tried.
Wait, is two tabs unusual? Like sure the default among my friends was one, but two is for when you really want to experience it and is more for constructive trips or to hallucinate and three is for when you need even more but you’re playing with fire there
I mean it depends on the person and the dose on the tabs. Like most recreational illegal drugs, it’s hard to know how much is actually present on the tabs.
Many times drugs are diluted at various steps of transport and selling. Though it is harder to do that to a drug already on paper like this.
Well literally anything can be addictive. People are addicted to gambling, to buying things online. To buying action figures or labubus.
But because lsd does not cause euphoria effects, it’s not typically considered chemically addictive. But there is not a complete consensus on this in the scientific community. Because it can still be behaviorally addictive.
But as I said. Literally anything can be behaviorally addictive so that’s almost a moot point.
Lsd is often distributed and consumed via small paper squares called “tabs” that’s made on blotter paper. The paper is thick like cardstock. Sometimes with colorful psychedelic artwork printed on it.
The lsd is diluted in a solution and the paper is soaked in the solution.
The tiny microscopic lsd crystals deposit on the paper. The blotter paper is divided into
1cmsquares. Correction. 5mm squaresLsd is neutralized by many chemicals , including chlorine (found in tap water) and stomach enzymes. It cannot be swallowed and still have an effect. Unless mixed with other compounds. This property was for dmt/ayuhasha and not lsd. Apologies. Chlorine can neutralize LSD and is found in tap water but I can’t find the resource for how much chlorine is in an average ml of tap water and how much is needed to neutralize 100ug LSD on a paper tab, right now, so I’ll retract that statement until I feel like digging more for the research on it.To take LSD, a person will place squares (typically one square is 1x 100ug dose) of the paper on the tounge or under it. And hold for about 5 -15 minutes. Some people take more than one. It can’t kill you. There is no overdose . But it can lead to accidents in high doses that can kill you. So it’s not risk free even if health risks are low.
Also I said ug. Not mg. The lsd drug is very unique in that it has high potency at micrograms. Fentanyl is another drug that has that property . But it is rare.
The lining of the mouth (mucus membranes) allows for easy transfer of the drug into the blood stream. That’s true for a lot of drugs actually.
This is why lsd has such a unique drug delivery method though.
It can’t be swallowed andit should be used in very small doses.Lsd is also very resistant to degredation. Oxygen, sunlight, and neutralizing chemicals like chlorine can degrade it. But if it’s stored properly it can last a very very long time. This is another rare property it has. Many other drugs degrade even when stored in air tight containers in dark and cool environments (like opiates).
It’s also clear, tasteless, and no odor.
I’m a perception researcher and , of course, this would be a drug on my radar. So I know quite a bit about it but I’m not a pharmacologist , I’m a cognitive researcher. I’ve given a lecture on psychedelics. It’s a fascinating topic.
Also I’m generally interested in psycho-pharmacology because , well, it’s interesting.
If you want to learn more interesting facts about LSD and other psychedelics, ask away.
**Guy in picture has two tabs (squares of blotter paper) on his tongue and is wearing sunglasses because lsd dialates your pupils and makes your eyes sensitive to light.
LSD absolutely can be swallowed, I don’t understand where all these myths come from and how they keep being propagated over decades and decades when it is a very simple thing looking it up.
Also, LSD is not crystallizing onto blotter. It is absorbed into the paper fibers from a solution. That is not how crystallization works.
Jesus there is more… Chlorine can degrade LSD under certain conditions, but trace chlorine in tap water does NOT reliably neutralize it in vivo.
LSD is chemically fragile. It degrades with light, oxygen, heat, acids, bases, and oxidizers. What you are saying is the opposite of how chemists describe LSD.
lol, sure you are.
What would you call the structure of the lsd molecule that deposits on the paper?
It is refered to as a crystalaline structure in papers.
Nothing I said about long term storage contradicts the specifics of the things that do break it down.
Incorrect about acid in the stomach. Most DOX and nbome chems are neutralized by stomach acid and during the mid 2010 acid drought swallowing tabs was considered the simplest way to avoid unwanted DOX trips.
Source: the hundreds of tabs that I swallowed and still had a good time
Edit: Tons of chemicals are active on the hundred microgram scale. Most benzos, nearly all psychedelics, a handful of antipsychotics ect. And if we go active at >10mg, which is impossible to dose without a .000 scale, the list gets even bigger. I appreciate the attempt at an informative post but it’s got a few dangerous points of misinformation.
I’m concerned that somebody giving lectures about this topic is as uninformed as you seem to be. Have you taken acid? The subjective experience is as important as the objective. It’s like listening to my cop uncle talk about weed but couched in academia.
I took DOC back in the 00s (on purpose) and it was an extremely wild 20-some hours. Second weirdest thing I’ve done (the weirdest is Foxy by a WIDE margin,) but I still had a relatively good time due to having a great and comfortable set and setting. By hour ten, I was VERY ready to be done.
I was too poor to care, been on plenty of non acid trips on chems that lasted wayyy too long. Some were really fun, some were abject terror. Never got to try foxy sadly. MXE was the strangest chem I’ve tried and holey hell, I turned into an interdimentional worm crawling through the multiverse. It was super overwhelming.
I never tried MXE! I wanted to as I have enjoyed ket in the past, but the times I was offered MXE, I just eas not in the right headspace/environment.
Foxy is fucking insane. It had the normal visual and auditory hallucinations, but it’s the only thing I’ve ever tried that gave me full on temporal distortions. My partner-at-the-time and I were listening to familiar music. The music would get lower in pitch and streeeetch out, each individual note playing for longer and longer, until the tone went back to normal and the notes stopped being played for so long. When it was low and slow, our bodies got soooo heavy, we would just lay on the floor. When the notes got fast and higher pitched, our bodies would be light with energy. VERY weird stuff.
MXE and ket are really different. The hole threshold and the visual nature are way stronger ime
Most drugs/medicines are taken in higher doses because the body filters or neutralizes the compounds so much that only a small portion gets into the blood.
That’s still different.
Even if the total quantity of the drug is small in the system once it gets there, it’s not the same as how LSD works. The drug, likely because of its similarity to serotonin and size , is readily absorbed into the blood stream and passes the blood brain barrier easily. It is not filtered out to a small percentage of it’s original dose like most drugs/medicines.
You surely are aware of this ?
There are very few drugs that can work in small dosages like LSD. As I said, fentanyl is one.
Drugs like DMT /Ayahuasca also can’t be ingested unless they are mixed with a maoi inhibitor.
Most psychedelic research chemicals (nbome) are much different than lsd with different pharm and effect properties.
It’s possible that LSD is released more quickly on the tongue than nbome drugs. So as soon as it hits the tounge the drug is delivered. I don’t think there is research on this. But I’ll look into it. I do know that the first trip was caused by a small contact of the drug on someone’s hand. That the cleaned off immediately. And it was enough time to absorb a substantial amount of the drug.
I heard women would put on lipstick and smear LSD on the front and kiss police during protest to dose them. If That happened it might support a very fast delivery.
I can’t find the source right now to verify the story. I’ll keep looking. Maybe I have details wrong. Maybe it was Charles Manson instructing women to do this. Does this story sound familiar to anyone ? I’ll have to find the source and verify.
But my point is.
This idea that it’s not neutralized in the stomach is false. There is plenty of research on that.
Look up Clonazepam, I’m not going to argue with somebody that is as confidently incorrect as you are. I have a decade and a half of subjective experience and personal research into the chemicals I have put into my body, and spent countless hours talking with people that know even more than I do. Yes, LSD is very active in small amounts. So are plenty of other chemicals and calling it unique because of that is incorrect.
Also, stomach acid does nothing to neutralize LSD in any meaningful way, please stop saying that. You’re entire last 2 paragraphs are unsubstantiated myths and things only squares believe. The amount of LSD that Hoffman splashed on his hand likely contained thousands of doses.
I HAVE EATEN HUNDREDS IF NOT THOUSANDS OF HITS OF LSD AND SWALLOW ALMOST EVERY SINGLE ONE OF THEM. SWALLOWING LSD DOES NOT PREVENT IT FROM WORKING. I WILL GIVE YOU TABS TO FUCKING TRY IF YOU WANT
Yeah this bozo has no clue what they’re talking about.
So take lsd and go star gazing.
Yes, but… it’s really hard to stay focused. Everything is kinda awesome to look at, so I have forgotten about the stars and zoned on my surroundings or my hand or a hundred other things. I like tripping in the woods or at the beach best personally.
Novelty is a common effect that people don’t talk about much. Essentially it makes everything seem new and novel.
What’s interesting is, in the brain there is a specific spike in electrical activity (called event related potential, or ERP) that happens when you look at something new and unexpected. Some call it the novelty indicator. Designated P3a.
You can measure it with eeg equipment (electrodes on the scalp).
I’d be really interested to see if that ERP is happening more on LSD. It might shed more light on the mechanisms of the drug. If it doesn’t happen, then it would challenge the theory of what the P3a is.
I personally think LSD has a lot of potential to be used to research perception processing in the brain.
Too bad it’s basically impossible to get approval to use it for that reason.
https://en.wikipedia.org/wiki/P3a
hell yeah
I believe the phrase is taking an lsd
They’re divided in 0.5x0.5 cm.
You can totally eat a tab and still get high.
Nowadays is hard to find 100ug doses. The minimum I had found is 150ug. Anything over 400ug isn’t LSD but Nbomb that is dangerous and should be avoided.
Ugh I do not miss 25i. Put a blotter on my tongue, taste it IMMEDIATELY, spit that shit out.
(This might have been mentioned and crooner definitely already knows this, but to others interested: LSD has zero taste at all. It just tastes like the paper it’s on (or gummy, faint grain alcohol if you’ve got a vial, etc)
I gave up on LSD because it lasted way too long and finished not enjoying it, until talking with a friend I commented that I also hated the sour flavor of it and he was like dude that was nbomb not LSD. Then he gave me some actual LSD and it was way more pleasure experience, not as high, but didn’t extend as long and the landing was confortable.
Bitters a spitter, gimme my money back
Ah yes you are correct. I definitely mis reported the size. It’s 5x5mm
Honestly, damn. That sounds like a very interesting topic. If I wanted to learn more what resources would you recommend? (preferably textbooks/articles)
Erowid.org.
Textbooks don’t really exist about this stuff, unless you’re like a pharmacology student and reading at that level.
Erowid also has free versions of PiHKAL and TiHKAL, Alexander Shulgin’s two books which are fucking awesome
I would take whatever this wall-of-text person is saying with a grain of salt. Erowid, in and of itself, isn’t a scientific source, but if you go to a page for any specific chemical, you’ll find a list of links that include scientific studies in journals, etc. as well as primary sources like experiences.
Thank you!
This person is an unreliable source fr information on LSD.
https://m.psychonautwiki.org/wiki/LSD
https://erowid.org/chemicals/lsd/lsd.shtml
You know there isn’t much in a single location aside from Wikipedia.
In textbooks I’ve come across , there is discussion of the pharmacology properties or a brief note about counter culture and general effects.
There is limited research on the drug as it’s been black listed for almost 50 years and even now, it’s primarily only researched for terminally ill people/mental health. Only a handful of those studies exist and none use double blind controls so the science quality is poor.
I myself am not convinced it has mental health benefits due to the way the drug works. It does however have strong suggestive effects meaning the drug itself promotes placebo/expectation effects.
The lecture I put together for my class (perception and sensation ) pulled info from a wide range of resources.
However there is one organization trying it’s best to do modern research and they have done some MRI studies. There was also a study on LSD and synesthesia which sheds a lot of light into the mechanisms. MAPS is the organization. https://maps.org/
They have videos on YouTube with researchers discussing the research and studies they have done. But they mostly focus (last few years at least) on it’s use in mental health.
The drug property information I know about is mostly pulled from old research from the 60s before the research bans. A lot was done on animals to understand dosage and half life. The cascade effects of how this drug works are still not really understood. We do know that the drug is similar in structure to serotonin. But there are still a lot of unknowns.
Let me dig around for my resource links. I have a few interesting studies I found when preparing the lecture, including the synesthesia one, and I’ll organize it all and I’ll put a link up to a g drive with it.
The lecture I did was 3 hrs long about hallucinations with a chunk dedicated to psychedelics. It did rely on other lecture materials to understand or otherwise id just put it up. (It was the final lecture for the class so it referred back multiple times to previous lessons). But maybe I can re-write it a bit. I’ve honestly been thinking of turning it into a video for a while because there are so few resources out there that review it more broadly. And a hell of a lot of misinformation about hallucinations and psychedelics.
Basically this lecture was on hallucinations and the primary causes and how each of these causes relies on the same root changes in brain processing.
For instance. You are driving on a country road at night. Vigilant to look for deer. Multiple times you were sure you saw an animal near the road but soon realized it was a fence post. Or an old glass bottle reflecting your headlamps. But for a split moment you did see an animal there before you corrected the perception.
What ultimately caused that is what causes hallucinations in other situations. Like schizophrenia and drug use.
So we circle around neuroscience, psychiatry, physiology, and pharmacology. As well as cultural impacts influencing the experience of hallucinations or psychedelics.
This is getting long. Apologies. The lecture is 3 hrs and relies on many other hours of information. It’s a big topic.
All this and you don’t even link to erowid?
https://www.erowid.org/chemicals/lsd/lsd.shtml
You don’t seem like a very good researcher.
also, PsychonautWiki…
https://m.psychonautwiki.org/wiki/LSD
Erowid is personal opinions of drug users.
I don’t lecture about how much acid you should drop or how to prepare for a trip. I give a lecture on the cognitive and physiological changes the drug causes.
I use scientific resources.
Other people are welcome to use personal stories and opinions to inform themselves but we don’t use anecdotes in academia because none of them can be verified and are heavily subjective.
Doesn’t mean they don’t have value. Doesn’t mean the information is false.
It just means it’s not scientific.
Among other things, including many links to scientific resources.
This is such a bad take that I again question your research methods.
Erowid is not a scientific resource.
Just because some people refer to scientific articles in their explanations does not mean, it, itself, is a scientific resource.
For instance. What I posted in the comments is not a scientific resource.
Even if I used links to actual resources. The resources are. But my comment is not.
Because it is not verified or peer reviewed.
Opinions, even those founded on science, are not scientific resources unless they meet other standards.
https://www.erowid.org/references/refs.php?S=lsd
Yeah, why is that? My link has thousands of peer reviewed journal articles and you have provided nothing of the sort.
The definition of a scientific resource is a RESOURCE with scientific observations and reporting that is peer reviewed or has some official review process like a university website with scholars writing the information that is verified by other scholars.
It’s the review process by people who are authorities on the topic that make that distinction. Scholars. Other scientist.
A comment on social media and anecdotal websites hosting forums is not a scientific resource. It’s opinions.
As I said earlier. Something doesn’t have to be scientifically validated to be true or real.
But it does have to be science to be science.
More specifically, experiments must use the scientific method and specific research statistic computations to support hypotheses which then are used to create theories.
Erowid does not have a review process where a senior scientist reviews any of the things posted on it.
Neither does Lemmy or faceb9ok,
Why is review so important?
Because humans are biased and our own subjective interpretation of patterns and events is not objective.
Just to illustrate some of the ways our thinking and interpretation of events is flawed, see cognitive biases on wikipedia.
And there are way more than these. https://en.wikipedia.org/wiki/List_of_cognitive_biases
And have a look at memory errors while you are at it. https://en.wikipedia.org/wiki/Memory_error
Oh and the best one. Bias blind sight. https://en.wikipedia.org/wiki/Bias_blind_spot
None of us, and I mean literally no one, is immune from these problems. Not me. Not you.
It’s why the only way we know anything for sure is through scientific methods of investigation. And even those aren’t full proof against bias.
I’m sorry that you don’t like the very basic explanation I gave of the properties of a drug you like. Some how that’s offensive to you.
I don’t know what to tell you.
I did get a few minor facts mixed up and i corrected them in the text. I Left in the original text and I crossed it out so that people could see I made a mistake and fixed it. Nothing I said was a huge big mistake about the drug. I misquoted the size of the tabs (10mm vs 5mm) and I was mistaken about it being neutralized in the stomach.
My gawd. Lock me up and send me a $500 fine. Jesus.
Maybe reflect on why it’s so important to you that your narrative of what the drug is, is being attacked from simple facts about how it works.
Why do you care how it works ? Why are you so invested in this? Why does it make you angry when someone explains the drug from a scientific perspective ?
If you don’t want to hear the scientific perspective then just ignore it.
It’s what a lot of people do.
FUCKING EROWID
How much acid have you taken yourself? Because it definitely works when swallowed.
After re checking this information, I believe I was confusing DMT and LSD properties of not being active when ingested.
I remembered DMT can’t be ingested but I was sure it was true for LSD. But I was mistaken. LSD is neutralized by base not acids.
DMT can be ingested so long as an MAOI is also present in the system. That’s literally what Ayahuasca is.
That’s literally what I said
You literally said DMT cannot be ingested what are you talking about?
And where do we get it 😂
Dark web
Don’t even have to go that far. LSD variants like 1V-LSD can be purchased on the clear web with a credit card. Took about 1 week to be delivered from Canada to the US, and was the most potent acid I’ve ever tried.
Wait, is two tabs unusual? Like sure the default among my friends was one, but two is for when you really want to experience it and is more for constructive trips or to hallucinate and three is for when you need even more but you’re playing with fire there
I mean it depends on the person and the dose on the tabs. Like most recreational illegal drugs, it’s hard to know how much is actually present on the tabs.
Many times drugs are diluted at various steps of transport and selling. Though it is harder to do that to a drug already on paper like this.
You can definitely swallow it
Your stomach acid will definitely neutralize it. But after having it on your tongue for a while the drug has been deposited into your system.
You’re confidently wrong:
https://www.sciencedirect.com/science/article/pii/S2772632023000338
Mate the first line of that publication is flat wrong
LSD is not addictive. I’m not going to bother reading any farther after such a ridiculous claim.
Couldn’t help myself, this is 2 sentences later
How do these people take themselves seriously!?
Well literally anything can be addictive. People are addicted to gambling, to buying things online. To buying action figures or labubus.
But because lsd does not cause euphoria effects, it’s not typically considered chemically addictive. But there is not a complete consensus on this in the scientific community. Because it can still be behaviorally addictive. But as I said. Literally anything can be behaviorally addictive so that’s almost a moot point.
I trust them on chemical properties and pharmacokinetics
However, here’s another paper:
https://pmc.ncbi.nlm.nih.gov/articles/PMC6494066/
That is incorrect